The initial areas of development for infirst Healthcare focused on medications to treat Common Cough and Inflammatory Pain conditions. Treatment of everyday GI symptoms has since been added to the portfolio. Common Cough and pain as well as GI symptoms are among the most common ailments when it comes to self-medication but also the most common symptoms presented to General Practitioners (GP’s).
Cough affects most consumers and patients and a significant proportion of sufferers experience unproductive cough symptoms, sometimes lasting for weeks and months, long after any underlying infection has gone.
In a market defined by products with variable effectiveness, many of which have never been clinically assessed and which can cause uncomfortable side effects, including misuse and abuse (because of their narcotic /opioid nature), sufferers may be found to adjust their lifestyles, avoiding theatre and concert visits, or social gatherings, in order to cope with their symptom.
Treatments for cough, which have been assessed in either clinical trials or ‘real world’ observation studies and which are non-narcotic / non-opioid, therefore define the agenda for infirst Healthcare's cough programme.
Similarly pain and inflammation are complex and multi-facetted conditions that are not always well served or well looked after. For example, acute inflammatory joint pain, which is a feature of flare-ups of long-term musculoskeletal conditions or following trauma, is poorly served.
Each year around a fifth of the population consults their general practitioner (GP) about a painful musculoskeletal condition. This amounts to over 100,000 consultations a day. Despite some significant progress in the long-term treatment of conditions such as osteoarthritis (OA), treatments to arrest pain during acute flare-ups are limited and are known to be accompanied by risk of side effects.
As a result, The Department of Work and Pensions estimated that 36 million working days were lost because of OA in 1999-2000 in Great Britain.
infirst Healthcare aims to take well known drugs, refine them and make them more fit for purpose, more specific for the pain which comes with inflammatory surges, so that acute and flaring pain can be effectively treated.
Everyday digestive Symptoms
Digestive health complaints can have many reasons ranging from diet to physiologic illness to functional disorders to stress and environmental causes. While complaints commonly vary in frequency and can be recurrent, most symptoms are transient in nature, yet bothersome and painful, effecting quality of life. infirst believes that treatments to relieve symptoms should be effective and fast, yet appropriate with regard to the systemic impact. 60% of the US adult population will experience some type of gastroesophageal reflux disease (GERD) within a 12 month period and 20-30% will have weekly symptoms.
Coughing has effected sleep in nine out of ten adults (89%)